The Sooners eclipsed the league record of 37 points set by Texas against Oklahoma in 2004 and matched by Oklahoma against Texas A&M in 2008.
Ryan Spangler scored a season-high 20 points, Buddy Hield scored 15 points and Isaiah Cousins added 13 for the Sooners (13-7, 4-4 Big 12), who had lost 4 of 5, with three of the losses against ranked opponents.
Texas Tech upset Oklahoma 68-60 in Norman last year, but the Sooners had this game in hand quickly and held Tech to 21 percent shooting.It was the worst margin of defeat in Texas Tech coach Tubby Smith's career. Tech (11-10, 1-7) was coming off a win over No. 9 Iowa State last Saturday that snapped a six-game losing skid.
Texas Tech had just seven points nearly 14 minutes into the game. Oklahoma's Frank Booker drained a 3-pointer that put the Sooners up 22-11 with about 5 minutes left in the first half.Hield, bottled up for most of the first half, made a 3 with 3 seconds left to give the Sooners a 37-16 lead at the break. Spangler had 12 points and three blocks in the first 20 minutes.
Oklahoma held Tech to 25 percent shooting before the break. Tech barely avoided its lowest-scoring half of the season, eclipsing the 14 the Red Raiders scored in the first half against TCU on Jan. 17.
Woodard dropped a 3-pointer in just under four minutes into the second half, and Khadeem Lattin had a dunk on the fast break to put the Sooners up 53-17 with 15:25 to go.
Texas Tech's first field goal of the second half came with 11:58 remaining. The Red Raiders shot 18 percent in the second half.
Texas Tech: Oklahoma was Tech's fifth consecutive ranked opponent. ... The Red Raiders missed all five of their 3-point tries in the first half. ... Myles Turner, who entered the game as the league's block leader with 3.0 per contest in Big 12 play, had none. ... Tech had two assists and 17 turnovers.
Oklahoma: The Sooners went scoreless for the first three minutes of the game, but rallied and shot 54 percent in the first half. ... Lattin had a career-high five blocked shots. ... It's the fewest points Oklahoma has allowed since 2007 when the team held Norfolk State to 36 and TCU to 35.
Texas Tech: At West Virginia on Saturday.
Oklahoma: At Oklahoma State on Saturday.
Follow Cliff Brunt on Twitter: www.twitter.com/CliffBruntAP.